18 people are killed and some others receiving treatment at the hospital after the vehicles they were travelling in were involved in an accident at Sarekyekura, a farming community near Fufulso in the Savannah Region.
It was gathered that those who died included 12 males and four females including a child.
Many others are said to be in a critical condition after they sustained varying degrees of injuries.
The Savannah Regional Fire Commander said both drivers died on the spot with two other people dying at the health facility they were sent to.
Meanwhile, 45 injured persons are currently receiving treatment at the Buipe Polyclinic and Holistic Medicare Hospital while all 16 bodies have been deposited at the Tamale Teaching Hospital.
The Regional Fire Service Commander is appealing to the government for rescue equipment in the region.